To protect clean competition and the integrity of sport and prevent doping in the United States with a performance-enhancing substance, the USADA provides education, leads scientific initiatives, conducts testing, and oversees the results management process.

[3][4] In 2001, USADA was recognized by the U.S. Congress as "the official anti-doping agency for Olympic, Pan American and Paralympic sport in the United States.

"[5] While USADA is not a government entity, it is partly funded by the Office of National Drug Control Policy (ONDCP), with its remaining budget generated from contracts for anti-doping services with sport organizations, most notably the United States Olympic and Paralympic Committee (USOPC).

[8] One of the major adjustments made to the Code by USADA included reducing the standard of proof required in doping-related adjudication.

After modification, USADA reduced the standard required to establish a doping violation to "comfortable satisfaction of a hearing body".

The Code is the core document that harmonizes anti-doping policies, rules, and regulations within sport organizations and among public authorities around the world.

It works in conjunction with five International Standards, which aim to foster consistency among anti-doping organizations in: testing; laboratories; therapeutic use exemptions; the list of prohibited substances and methods; and the protection of privacy and personal information.

[13] USADA collects both blood and urine samples during in-competition and out-of-competition tests, which can occur at any time, at any location, and without advance notice.

According to the Code, an ADRV consists of the following: When evidence meeting one or more of the above violations is found, an independent anti-doping review board will make the recommendation whether USADA should move forward with a sanction.

[27] USADA supported research in a variety of areas, including anabolic steroids, growth hormone, oxygen transport-enhancing substances, genetic doping, ethics, and Isotope Ratio Mass Spectrometry.

[29] USADA created an online resource designed to provide athletes with the best possible information to evaluate the risks associated with the use of supplements.

[citation needed] USADA's UFC Anti-Doping Program began testing athletes both in and out-of-competition at increasing rates.

[31] In January 2021, USADA announced that UFC fighters would no longer be punished for cannabis use except in extreme cases where clear signs of intoxication were present at the time of a fight.

[32] In October 2023, USADA announced that they would no longer oversee the UFC's anti-doping program once their contract with the company ends in December 2023.

[37]: 572 The District Court found, that as a member of USA Cycling, Armstrong was thereby beholden to the USADA Protocol, which required that all contested charges of doping be tried through NAS and CAS arbitration.

In response, Armstong was given a life ban by USADA from competing in any sport that uses the World Anti-Doping Code, effectively ending his competitive career.

The evidence also includes direct documentary evidence including financial payments, emails, scientific data and laboratory test results that further prove the use, possession and distribution of performance enhancing drugs by Lance Armstrong and confirm the disappointing truth about the deceptive activities of the USPS Team, a team that received tens of millions of American taxpayer dollars in funding.The Bay Area Laboratory Co-operative (BALCO) was a San Francisco Bay Area business that supplied anabolic steroids to professional athletes.

BALCO was founded by Victor Conte, who sourced the drugs from Illinois chemist Patrick Arnold and distributed them with the help of personal trainer Greg Anderson.

The syringe went to Don Catlin, MD, the founder and then-director of the UCLA Olympic Analytical Laboratory, who had developed a testing process for the substance, tetrahydrogestrinone (THG).

[citation needed] A number of athletes, including Marion Jones, Kelli White, British sprinter Dwain Chambers, shot putter Kevin Toth, middle distance runner Regina Jacobs, and hammer throwers John McEwen and Melissa Price were subsequently incriminated in the investigation.

[citation needed] In April 2019, UFC bantamweight champion TJ Dillashaw voluntarily relinquished his title, after adverse findings in a USADA test before his fight with Henry Cejudo.

[42] WADA stated that it discovered at least three cases of athletes who had violated anti-doping rules and were permitted to compete for years while serving as undercover agents for USADA.