Since its inception la società arancione (Orange Society) founded on April 21, 1921, has been characterized by its European inclinations, being the city historically a crossroads of historical-religious paths to and from the geographical areas of the Old Continent.

It is no coincidence that among the protagonists of the birth of l’Arancione you will find the Hungarians Árpád Hajós and János Nehadoma, with the jersey inspired by that of Holland, which, like the city of Pistoia, boasts a strong floriculture.

From 1946 to 1956–57, the team fluctuated between the leagues until Vannino Vannucci rose to the presidency in 1956–57, and Pistoiese became a "Jewel in the Nile" at a cost of 100 million lire.

An excellent end to the season brought the team to a 9th-place finish in Group A, which was three points ahead of the relegation playoff.

Still, disappointing results and a last-place position in the Lega Pro Prima Divisione table led the club to replace him with Salvatore Polverino later in October.

In the summer of 2009, Pistoiese was not permitted enrollment in Lega Pro Seconda Divisione due to inadequate finances.

In January 2021, the club was acquired by German entrepreneur Stefan Lehmann, the first foreign owner in Pistoiese history.