In 1843 the title "Queen conceived without original sin" was added to the Litany of Loreto, partly through the efforts of Antonio Rosmini, founder of the Institute of Charity.

[1] That same year, the twenty-three bishops present at the Sixth Provincial Council of Baltimore chose "Mary conceived without sin" as the patron saint of the United States.

Pius begins by acknowledging the numerous requests received by both his predecessor, Pope Gregory XVI, as well as himself for a declaration of the dogma.

The positive response to Ubi primum led to the 1854 bull Ineffabilis Deus, which defined the dogma of the Immaculate Conception.

[5] This approach was quoted by Pope Pius XII in 1946, when in Deiparae Virginis Mariae, he inquired from the bishops about a possible dogma of the Assumption of the Virgin Mary.