Udokaha Jacob Esuene listenⓘ (1936 – 1993) was a Nigerian air force officer who was Military Governor of South-Eastern State (later renamed Cross River State) between May 1967 and July 1975 during the military regime of General Yakubu Gowon.

[2] Esuene, who was of Ibibio ethnicity, was a fighter pilot before being appointed governor of South-Eastern State.

[3][4] Esuene was dismissed by General Murtala Muhammed when he seized power in July 1975, was charged and found guilt of illegally enriching himself while in office, and was dismissed from the military.

[5] The dismissal was, however, reversed by the Armed Forces Ruling Council led by the then Military President; General Ibrahim Babaginda.

[3] After his death, his wife Helen Esuene was appointed Minister of State for Health, and later Minister of Environment and Housing in the Cabinet of President Olusegun Obasanjo between 2005 and 2007.