Uesugi Norimasa (上杉 憲政, 1523 – April 13, 1579) was a daimyō of feudal Japan from Yamanouchi branch Uesugi clan and held the post of Kantō Kanrei, the shōgun's deputy in the Kantō region.

He was the adoptive father of Uesugi Kenshin, one of the most famous warlords in Japanese history.

His adopted brother, Uesugi Norihiro, succeeded his father as head of the clan.

In 1551, he was defeated once again at Siege of Hirai castle by Hōjō Ujiyasu, and fled to Echigo Province, where he sought asylum with his vassal Nagao Kagetora.

Norimasa was forced to name Kagetora his heir, and to grant him the titles of Lord of Echigo and Kantō Kanrei.