The Ukrainian Catholic National Shrine of the Holy Family is located immediately west of the Catholic University of America campus and roughly 250 feet north of the Saint John Paul II National Shrine.

The Basilica of the National Shrine of the Immaculate Conception is located roughly a half a mile south along the east side of Harewood Road.

Eparch Constantine Bohachevsky, the first Ukrainian metropolitan bishop in the United States, created Holy Family Parish in 1949 to serve the Ukrainian Greek Catholic population in Washington, D.C., as the nearest Ukrainian parishes to the Washington area until then had been outside of the District of Columbia.

The parish would relocate four times until acquiring its current site 1975.

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