It was the depot for trams operating services to Pyrmont, Ryde, and Erskineville.

It was situated on the eastern side of Harris Street adjacent to the Darling Harbour railway line.

[1] The depot closed on 27 June 1953 following the decision to replace trams with buses on the Drummoyne service.

[2] The staff of 250 drivers, conductors, inspectors, and maintenance men, with 21 trams, have been transferred to other depots.

[3][4] The tram sheds were converted to offices in 1981 as part of the Powerhouse Museum development.