Also, The two sons of al-Hadi, Isma'il and Ja'far married Harun-Rashid's daughters, Hamdunah and Fatimah respectively.
Her husband was born on the same day when her father died and her uncle ascended to the Caliphate.
Her uncle, caliph Harun al-Rashid had nominated his two elder sons Al-Amin and al-Ma'mun as heir.
[3][1] Her husband al-Ma'mun became caliph after the death of her cousin and brother-in-law al-Amin.
[4] Umm Isa was related to the Abbasid ruling House paternally.