[12] In February 2018, following a five-year hiatus, the duo announced they would be reuniting, and are set to embark on a world tour, as well as release new music.

The success of this collection (which was certified gold) led the label to produce Los Reyes del Nuevo Milenio, the first album by Wisin & Yandel.

On November 7, 2007, Wisin & Yandel released the album Los Extraterrestres, which featured collaborations with international artists like Eve and Fat Joe.

The album was received positively by the Puerto Rican media, with mainstream newspaper Primera Hora awarding it a score of 4 out of 5.

[17] After organizing concerts throughout Latin America and Europe, Wisin & Yandel noted that they would like to expand their markets to Africa and Australia.

[18] On June 2, 2008, the duo began a tour to promote Wisin vs. Yandel: Los Extraterrestres, Otra Dimensión, visiting several radio stations in Puerto Rico.

[20] On June 12, 2008, they traveled to Los Angeles to attend the BMI Latin Awards, in which they received a nomination for Writer of the Year.

The production featured several Latin American artists including Daddy Yankee, Don Omar and Héctor el Father along Jamaican musicians like Inner Circle, Bounty Killer, Elephant Man and Wayne Wonder.

In September 2014, they both confirmed they were working on a new track that would premiere and be performed for the first time on Yandel's De Líder a Leyenda tour on October 4, at the José Miguel Agrelot Coliseum in San Juan, Puerto Rico.

On September 8, 2017, Yandel released the single "Como Antes" from his new album featuring Wisin, which came after their long-awaited return as a duo.

[32] In May 2018, Wisin & Yandel announced on their Instagram a concert for November 30, 2018, at the José Miguel Agrelot Coliseum in Puerto Rico.

On December 14, they released their latest album Los Campeones del Pueblo which features collaborations with many artists including Ozuna, Maluma, and Bad Bunny.

At the same time, they released two compilation albums Como en los Tiempos de Antes and Juntos Otra Vez.