[6][7][8] Recorded at London Bridge Studio, Uncle Anesthesia was produced primarily by Terry Date and Soundgarden vocalist Chris Cornell.

"[15] The St. Petersburg Times wrote that "vocalist Mark Lanegan croons fairy tale lyrics that melt through a sonic wall of guitars and percussion.

"[18] The Dayton Daily News concluded that "if Jim Morrison had joined a garage band instead of the jazz-trained Doors, it might have sounding something like Screaming Trees.

"[20] The Washington Post determined that "Gary Lee Conner can tear off a screeching lead or stomp a wah-wah pedal like any halfway-initiated Black Sabbath disciple, but he's not merely a piledriver; his atmospheric playing on tracks like 'Bed of Roses' give them unexpected delicacy.

"[21] The San Diego Union-Tribune stated that "Lanegan's spooky, back-from-the-crypt vocals and Gary Lee Conner's luminous guitars give this album an otherworldly glow.