It is located at 603 Main Street, in a classical revival-style building designed by the Office of the Supervising Architect under James A. Wetmore,[2] and completed in July 1931.

[2] The Racine Main Post Office is a three-story rectangular building, located two blocks from the shore of Lake Michigan.

The building is faced primarily with Bedford limestone from Indiana, except for parts of the obscured south facade which are covered with red brick.

At the east end, facing the parking lot, a retaining wall has been painted with a mural that features a bald eagle in front of the rising sun, labeled "Racine - A Nice Place to Live".

Aside from the front counter and mailbox area, the majority of the building consists of large open spaces where mail is processed.

The second-story workroom is lit by two large skylights, which occupy a square area of the roof where the top floor is cut out of the rectangular structure.

[10][14] A proposal in 1991 would have moved the city's main post office to a triangular lot along State Street, but this plan was never put in place and that site is now home to Dr. Martin Luther King, Jr.