Universidad Mayor is a private university in Santiago, Chile.

It was founded in 1988.

Universidad Mayor opened its first academic programs in 1988 with bachelor's degrees in Architecture and Engineering with 3 majors; Industrial Engineering, Computer Science and Electronics Engineering which were offered at its Main Campus in Américo Vespucio.

Within a few years, Universidad Mayor became the first private university in Chile to offer Agronomy and Forest Engineering (1989), Veterinary Medicine (1991), Dentistry (1997) and a Medical Residency Program (1998).

It is accredited by the United States Middle States Commission on Higher Education (MSCHE).