University High School is a public, four-year high school located in Orange City, Florida, United States.

[2] As of 2010, it was the largest high school in Volusia County by enrollment.

About 500 students at the new high school come from DeBary, about 500 from Orange City, another 250 from the unincorporated area around Orange City, and about 900 from Deltona.

The school has an elaborate advanced-placement program.

University High School is partnered with the University of Central Florida, Stetson University, and Embry Riddle Aeronautical University in sponsoring two academies, the STEM Academy (Science, Technology, Engineering, and Mathematics), and the Academy of Finance.