The hospital is operated by a charitable foundation established in 1354 through the will of Anna Seiler, a wealthy Bernese.

[3] It acquired its current name in 1531 when it occupied the buildings of the "St. Michaels Insel" convent.

As of 2016, the hospital employs a staff of 7,255 and provides care for 250,000 patients each year.

[8][9][10] The prominent physicians who have practiced in the Inselspital include Emil Theodor Kocher, the 1909 Nobel laureate.

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