The University of Brescia was officially established in 1982 with three Schools: Medicine and Surgery, Engineering, Economics and Business.

However, the creation phase lasted nearly two decades, so the first attempts to open university courses in Brescia go back to the 1960s.

A first initiative came from Ethan Doro, which opened negotiations in the early 1960s to set up a two-year course in Engineering as a branch of Politecnico di Milano.

In the field of economic studies, in 1964 a School of Industrial Administration was created, offering two-year courses.

The idea of setting up a university pole in Brescia, following the first failed attempt in the early 1960s, regained strength in the second half of the decade with the birth of the Consorzio Universitario Bresciano (CUB), promoted by the Provincial Administration, the Municipality of Brescia and the Chamber of Commerce.