The University of Sannio (Italian: Università degli Studi del Sannio, UNISANNIO) is a university located in Benevento, southern Italy.

In the three-year plan 1991–93, the Faculty of Science was set up with additional degree courses in Biology and Geology.

The Faculty of Economic and Social Sciences was managed by a Technical committee until 31 October 1994.

With the Ministerial Decree n.1524, of 29 December 1997, the University of Sannio was officially recognized and became autonomous as from 1 January 1998.

Since 2005, the University of Sannio is a partner of the Euro-Mediterranean Center for Climate Change (CMCC).