The Foundation Vice-Chancellor was Professor Fred Newton Binka, MBChB (Legon), MPH (Jerusalem), PhD (Basel) who served from March 2012 to July 2016.

In August, 2017, a new council was inaugurated with Justice Jones Victor Mawulorm Dotse as the chairman.

[10] In a special meeting held on June 3, 2022, the Governing Council of the University of Health and Allied Sciences[11] approved the appointment of Prof. Aziato as the new Vice-Chancellor.

[12] Effective August 1, 2022, Prof. Aziato assumes the prestigious position,[13] becoming the first woman and a nurse to hold the role of Vice-Chancellor in the history of the University.

[28] The REC is made of seven (7) Scientists/Academics and 8 Non-scientists; including A lawyer, Journalist, Religious Body Representing the larger Community, Sociologist, Educationist, Traditional leader, Public Health Expert and a Medical Doctor[28] The officers of the REC include the chair, Vice Chair and the Administrator.