Salvatore Boscarino, a professor at the University of Catania, held the first lesson, on 18 December 1967, titled "Elements of Architecture and survey monuments".

In 2001, the rector Alessandro Bianchi, professor of Urban Planning, who remained in office until May 2006, the date of appointment as Minister of the Italian Republic for the Transport of the Prodi government, changed the name of the University.

[2][3] The Mediterranean University has conferred honorary degrees on:[4] On 30 July 2013, in the presence of the Prefect of Reggio Calabria, Vittorio Piscitelli, a collaboration agreement was signed between the Mediterranea University of Reggio Calabria and the special agency Stazione Sperimentale per le Industrie delle Essenze e dei Derivati dagli Agrumi (SSEA).

[5][6] The agreement provides for an investment of 5 million euros in equipment, and the redevelopment of the SSEA experimental field to include laboratories for analysis and certification of essential oils and food ingredients.

Expresses opinions and proposals on the request, the destination and the filling of posts of professor and researcher role, limited to the scientific areas of expertise of the department.

[10] The partnership is characterized by a common scientific field of study that is the city and its multidisciplinary aspects, concerning the general theme of urban policy and planning.

The universities along Mediterranea that participating in the program are:[11] School of specialization for the legal profession (I and II year), with national programming exam: School of High Formation in Architecture and Archeology of Classical City Most of the students come from Sicily and Calabria, but there is a good percentage of students coming from other Italian regions.

In addition at the UNIRC are active, thanks to the Treaty of Friendship, Partnership and Cooperation between Italy and Libya, numerous scholarships for Libyan students who want to study in Italian universities.