One of the milestones for Roma Tre, since its foundation, as well as a guideline for its development, was its incorporation in the surrounding area, characterised by the reclamation of old buildings and school premises, transformed into facilities for study and research.

Roma Tre University takes part into a series of international university networks that share the task of promoting cooperative activities in diverse fields and seek to create a European area of communal higher education.

[31] The School of Law is constantly ranked among the top-five in the country with a note of AAA (Censis-La Repubblica),[citation needed] mostly due to the selective entry test and to the small-size of the classes.

Past speakers include Antonio Ruberti, the ninth President of Italy Oscar Luigi Scalfaro, the 49th Prime Minister of Italy Carlo Azeglio Ciampi, Leah Rabin, Shirin Ebadi, the member of the executive board of the European Central Bank Tommaso Padoa-Schioppa, the seventh European Commissioner for Research, Innovation and Science Philippe Busquin, the 264th Pope John Paul II, Kerry Kennedy, Marco Travaglio, the sixth President of the European Parliament Josep Borrell Fontelles, the 34th President of Chile Michelle Bachelet, the 11th President of Italy Giorgio Napolitano, and the 52nd Prime Minister of Italy Romano Prodi.

[citation needed] Notable alumni include: Andrea Alù, Alessandro Di Battista, Joseph Pace, Marco Lo Muscio, Raffaele Monti, Virginia Raggi, and Cinzia Giorgio.

Among the prominent scholars who have taught at Roma Tre University include Pier Luigi Luisi, Pierangelo Garegnani, Paolo Leon Andrea Riccardi, Luciano del Castillo, Giuseppe Conte, Giorgio Melchiori, Giacomo Marramao, Mario De Caro, Roberto Cipriani, Vittorio Cotesta, Amos Luzzatto, and Federico Schiano di Pepe.