The Southern Institute was granted a permit to operate a complete elementary course and the first two years of secondary education on May 29, 1927.

Two years later, on August 28, 1929, the government recognition of the secondary course was granted and the school produced fifteen graduates.

In 1933, with the increase in the school population, Southern Institute moved to its own two-story concrete building on Mabini Street.

In 1939, the Southern College began to offer the Junior Normal Course as there was a great demand for elementary school teachers then.

In 1959, the stockholders agreed to dissolve the original stock corporation and converted USP into a non-stock, non-profit foundation.

Oscar Jereza Sr., announced the decision reached by the Board of Trustees to temporarily stop operations in all levels at the Mabini Campus.

In June 1999, the College of Law re-opened and a new graduate program, Master of Science in Environmental Management, was offered.

On January 28, 2003, the Commission on Higher Education (CHED) issued a permit for USPF to open and conduct the First Year of the four-year Bachelor of Science in Nursing starting June 2003.

104 s. 2003 to conduct and operate the four-year Bachelor of Science in Information Technology (BSIT) course, effective SY 2003-2004.

On June 10, 2005, CHED issued Government Recognition to conduct and open the Post Baccalaureate Diploma in Community Development and Bachelor of Science Entrepreneurship.

On December 1, 2005, the Board of Trustees appointed Dr. Alicia P. Cabatingan as the new University President following the death of Dr. Ronald R. Duterte in November 2005.

In the same year, the university processed the accreditation of the School of Business and Management, the College of Computer Studies and Information Technology, and the Basic Education departments of the Mabini and Lahug campuses.

The SHS Lahug achieved a 100% TESDA NCII ASSESSMENT passing rate for all their Technical Vocational Livelihood courses.

Starting the second semester of School Year 2018-2019, the University was granted by CHED an authority to offer ETEEAP in Business Management courses.

In 2019, the Health, Safety, & Security department initiated the University Disaster Risk Reduction Management Team (UDRRMT) and completed installation of CCTVs in both campuses.

In December 2020, the PACUCOA recognized the Elementary School Lahug as the first Elementary program to have been granted LIII Reaccredited Status in Region VII and JHS Lahug as the first High School program to have been granted LIII Reaccredited Status in Region VII.

SHS Lahug continues to achieve 100% TESDA NCII ASSESSMENT passing rate for all their Technical Vocational Livelihood courses.

The School of Business and Accountancy Bachelor of Science in Entrepreneurship was granted a Government Permit effective First Semester of SY 2021-2022.

The Mabini campus underwent significant renovations in preparation for the PACUCOA Level II 2nd Reaccreditation, which was successfully conducted in the second semester of School Year 2020-2021. major in: major in: Department of Teacher Education Department of Arts & Sciences Certificate Courses The University of Southern Philippines Foundation Learning Resource Center is a Technical Education and Skills Development Authority (TESDA) Accredited Assessment Center that offers Technical-Vocational Education and Training (TVET) Programs.