For this recording, the band included second guitarist and co-producer Avi Bortnick and drummer Adam Deitch, both of whom appeared on Überjam.

The recording also features bass guitarist Andy Hess (who also played in Gov’t Mule).

A four piece horn section, arranged by Scofield, appears on six of the eleven tracks.

On AllAboutJazz Farrell Lowe begins his review “The Freaky Deaky is back!,” referring to Scofield's time playing with Miles Davis, “this is the most inspired playing I have heard from John Scofield in many years.”[2] “Scofield inhabits a place in which the cerebral and the funky ... form an alliance and work together for the common good,” Alex Henderson writes in his four-star-review on AllMusic, and concludes: “Up All Night is a consistently engaging addition to his sizable catalog.”[1] Whereas on JazzTimes Nate Chinen writes in his critique, “Scofield and crew acquit themselves flawlessly to the material, but ... there are no real clunkers on the album (despite a cheeky "Watch Out for Po-Po," which comes close).

The John Scofield Band Horn section (tracks 1, 4, 6-8 & 11) Additional musicians