In the late 2060s, Logan Ramsay is a law enforcement official working for the Gene Protection Agency (GPA), an organization established in the aftermath of a global famine known as the "Great Starvation", which resulted from an attempt to genetically enhance crops.

After recovering from severe flu-like symptoms and a notable increase in bone density, Logan discovers enhancements in his cognitive abilities, such as improved focus, comprehension, and memory.

When he investigates a disease outbreak in Glasgow, Montana, he discovers that Kara has begun dispersing the upgrade, while beneficial to some, proves fatal to others due to deleterious mutations.

In the aftermath, Logan develops a new version of the upgrade focused on enhancing empathy, aiming to address humanity's challenges without the extreme measures his mother and sister deemed necessary.

Choosing exile to protect his family, he leaves them a journal and a letter explaining his actions and his hope for a future where humanity can navigate its perils with compassion.