It contains only one species, Upiga virescens, the senita moth, described by George Duryea Hulst in 1900 and found in the Sonoran Desert of North America.

[4] The senita moth is light brown with wide white stripes traversing the body from head to wing tip.

[5] The abdomen of the female is covered with scales, called the posterior brush, which are used to collect pollen from senita cactus flowers.

[6] Eggs are laid singly on open senita cactus flowers, either on the petals, anthers, or the corolla tube.

They then bore an exit hole through the fruit and, at twelve to seventeen days of age, either pupate or enter diapause, a state of developmental dormancy, to overwinter in the stem of the senita and then emerge in a later flowering season.

[5] Pupation takes place in the cactus stem and adults emerge from exit holes created during the previous larval stage.

Females lay eggs on host plant flowers, and larvae feed off of the developing fruit inside.

[4] Oviposition takes place on senita cactus flowers, which open after sunset for six to twelve hours, from late March to September.

However, when accounting for variation in surface area, oviposition occurs more frequently on the anthers and corolla tube.

Larval survivorship is reduced by a low egg hatching percentage, corolla-induced mortality, resource-limited fruit abortion, and wasp parasitism.

[6][8] This mutualistic relationship is present throughout the senita moth's range, which suggests there is strong selective pressure on traits that maintain mutualism.