Upper Makefield is located in the Delaware Valley but is considered to be part of the New York metropolitan area.

Upper Makefield Township's multimillion-dollar homes, highly-ranked public schools, and relatively easy commute to New York City and Princeton led to its 2006 ranking as "Best Place to Live in the Suburbs" in Philadelphia magazine.

[3] The township is the Philadelphia area's second-most expensive suburb[4] and the 287th-wealthiest neighborhood in the nation with a mean household income of $306,081.

Past and present place names in Upper Makefield include Buckmanville, Dolington, Jericho, Lizette, Lurgan, Washington Crossing, and Woodhill.

On average, the wettest month of the year is July which corresponds with the annual peak in thunderstorm activity.

The plant hardiness zone is 6b with an average annual extreme minimum air temperature of -0.2 °F (-17.9 °C).

PA 232 utilizes Windy Bush Road as it crosses the northwestern part of the township on a northeast-southwest alignment.

Finally, PA 532 follows Washington Crossing Road on a southwest-northeast alignment across the southeastern portion of the township, reaching its northern terminus at PA 32 just shy of the Washington Crossing Bridge.