Tulpehocken is a name derived from a Native American language meaning "land of the turtles".

[2] The Seyfert Mill was listed on the National Register of Historic Places in 1990.

Portions of the Pennsylvania State Game Lands Pennsylvania State Game Lands Number 110 which also carries the Appalachian National Scenic Trail is located along the northern border of the township.

[8] Interstate 78 and U.S. Route 22 are the main highways serving Upper Tulpehocken Township.

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