Uproxx was founded in 2008 by Jarret Myer and Brian Brater, who previously co-founded the hip hop label Rawkus Records in 1996.

[5][6] In December 2014, Woven raised US$18 million in Series A funding with a portion of the capital allocated to growing Uproxx through staff hires and video development.

[17] In February 2024, Warner indicated its plan to sell its owned media assets, including Uproxx and HipHopDX, as part of a shift to focus on its music business.

[19][20] The new independent studio also reached a deal to represent Warner Music for all YouTube media sales in the United States.

[20][21] Elliott Wilson was also appointed editorial director of hip-hop journalism overseeing Uproxx, HipHopDX and Dime Magazine.

[9] In 2017, Uproxx created a piece of branded content for fast food chain Checkers featuring rapper Rick Ross.

[33] In 2022, Uproxx released a new web series titled Fresh Pair hosted by hip-hop producer Just Blaze and sneaker designer Katty Customs.