It is served by the District and Hammersmith & City lines between Plaistow and East Ham stations.

The station was opened by the London, Tilbury and Southend Railway (LTSR) in 1877.

Nowadays, the station serves Queens Road Market and Green Street.

Upton Park was the first station on the LT&SR to be built by a property developer.

Upton Park tube station appears in the English slang term, "He/She is Upton Park - two stops short of Barking", indicating that the individual in question is slightly mad.