Built by owner at the time, Lawrence Borg, The Uptown made its public debut on August 12, 1937, showing the film Ever Since Eve.

Ownership and management of the theater changed hands several times in the 1990s and closed in 2000 due to falling attendance and competition from other newer facilities.

[3] After purchasing the Uptown Theatre in 2000, real estate developer George Altamura announced in 2003 that he had partnered with several investors including Francis Ford Coppola in a project to restore the building as a live entertainment venue.

[8] Since reopening, the theater has hosted several hundred performers including Willie Nelson, Boz Scaggs, Leon Russell, Rosanne Cash, George Thorogood, Merle Haggard, John Prine, Emmylou Harris, Jerry Jeff Walker, Lily Tomlin, B.B.

King, Glen Campbell, John Hiatt, Los Lonely Boys, Cyndi Lauper, Lyle Lovett and Robert Cray.