[1] The genus was established by McAlpine for rusts on Acacia (Fabaceae, subfamily Mimosoideae) with teliospores that clustered at the top of a pedicel.

Some of these species infect plants in the family Mimosoideae including Acacia, Paraserianthes and Falcataria.

[2][5] Species include: The rust fungi in the genus Uromycladium typically form enlarged galls at the end of actively growing plant tissues.

[8] The galls of Uromycladium tepperianum have been reported to be used by moths in the families Gracillariidae, Tortricidae, Tineidae, Pyralidae, and Stathmopodidae as food sources and domatium for their larvae in Australia.

Erechthias mystacinella and Opogona comptella moth larvae from the family Tineidae have been reported to live and feed on the inside of Uromycladium tepperianum galls.