Holl started her career at TSV Uengershausen, before joining FSV Frankfurt, where she made her Bundesliga debut.

After the 2010–11 season she left Duisburg and signed a one-year contract at Bundesliga side SG Essen-Schönebeck,[4] after which she ended her active playing career.

Holl was Germany's third goalkeeper at the 2005 European Championship, winning her first international title without a single cap at senior level.

She made her debut for the German national team almost two years later in March 2007 at the Algarve Cup against France.

That year she also won the 2007 FIFA Women's World Cup with Germany, again as the team's third choice goalkeeper.