Uruguay competed at the 2019 Parapan American Games held from August 23 to September 1, 2019 in Lima, Peru.

[1] The country finished in 14th place in the medal table.

Henry Borges won the gold medal in the men's 60 kg event.

Gonzalo G. Dutra Irinitz won the bronze medal in the men's 100m breaststroke SB9 event.

[1] Uruguay competed in table tennis.