Running from 1915 to 1971, Intermedia was the second division from 1915 to 1941, and then became the third level when professional Uruguayan Segunda División was established in 1942.

[1] The most winning teams of the division were Colón, Mar de Fondo, Progreso, and Uruguay Montevideo with 4 titles each.

The first second division established in Uruguay, the Segunda División had been held since 1903, although it was contested irregularly.

[2] In 1932, football became professional in Uruguay so Primera División and Intermedia (which still remained amateur) lost their connection.

Complete list of champions, with missing information of runner ups and 3rd.