The border is paralleled on the Uzbek side by a road and railway line, and there is a major crossing point between Termez in Uzbekistan and Hairatan in Afghanistan.
As the village of Khwaja Salar could no longer be identified it was agreed that the boundary should meet the Amu River in the vicinity of Khamiab, Afghanistan.
[6] The easternmost section of the border (now forming part of the Afghan–Tajik boundary) was not finally delimited until 1893–95, with Emir Abdur Rahman Khan of Afghanistan agreeing to waive any claims to lands north the Amu River.
This agreement also stipulated the position of the land border in section east of Lake Zorkul up to China, with a series of boundary pillars subsequently erected.
[6] In 1921, a Soviet–Afghan treaty was signed whereby Russia agreed "to hand over to Afghanistan the frontier districts which belonged to the latter in the last century, observing the principles of justice and self-determination of the population inhabiting the same".