The Borders of modern day Central and South Asia were drawn by the British and Russian Empires during the great game.

[3] When the Russian Empire became the USSR hard borders were put in the region for the first time, Separating the Tajiks, Uzbeks, and Turkmen of Afghanistan with their Northern relatives.

Uzbekistan began playing a larger regional role in trade, cultural connections, and as a mediator in the Afghan conflict.

Usmonov had previously served as Deputy Minister of Foreign Affairs and ambassador to Pakistan (2020-24) and Egypt.

[16] The territories of Afghanistan and Uzbekistan were under a single control during the period of the Samanid, Ghaznavid and Timurid dynasties.

In 1750, the Treaty of Friendship between Afghan emir Ahmad Shah Durrani and the Bukharan khan Mohammad Murad Bek resulted in the Amu Darya river becoming the official border of Afghanistan that remains to this day.