Uzbekistan competed at the 2000 Summer Olympics in Sydney, Australia.

70 competitors, 52 men and 18 women, took part in 69 events in 12 sports.

[1] Men's 400 m Hurdles Men's 4 × 100 m Men's Discus Men's Javelin Throw Men's Hammer Throw Men's Long Jump Men's Triple Jump Men's Decathlon Women's 100 m Women's 200 m Women's 400 m Women's 4 × 100 m Women's 4 × 400 m Women's Heptathlon Men's Light Flyweight (– 48 kg) Men's Bantamweight (– 54 kg) Men's Featherweight (– 57 kg) Men's Light Welterweight (– 63.5 kg) Men's Welterweight (– 67 kg) Men's Light Middleweight (– 71 kg) Men's Middleweight (– 75 kg) Men's Light Heavyweight (– 81 kg) Men's Heavyweight (– 91 kg) Men's Super Heavyweight (+ 91 kg) Men's Kayak Singles 500 m Men's Kayak Singles 1000 m One female fencer represented Uzbekistan in 2000.

Men's 50 m Freestyle Men's 100 m Freestyle Men's 200 m Freestyle Men's 100 m Butterfly Men's 200 m Butterfly Men's 200 m Breaststroke Men's 200 m Individual Medley Men's 4 × 100 m Freestyle Women's 50 m Freestyle Women's 100 m Butterfly Women's 200 m Breaststroke Men