The V. G. Khlopin Radium Institute, also known as the First Radium Institute, is a research and production institution located in Saint Petersburg specializing in the fields of nuclear physics, radio- and geochemistry, and on ecological topics, associated with the problems of nuclear power engineering, radioecology, and isotope production.

[1] It is a subsidiary company of the Rosatom Russian state corporation.

This also included a factory in Bondyuga (Tatarstan), which was used by Vitaly Khlopin [ru] and others to generate Russia's first high-enriched radium compound.

[4] The Radium Institute under Abram Ioffe was relocated to Kazan in World War II.

[6] At the Radium Institute, the first European cyclotron was proposed by George Gamow and Lev Mysovskii [ru] in 1932, being constructed with the help of Igor Kurchatov, operational by 1937.