[4] It is located next to Amsterdam's A10 ringway in the southwestern part of the city, next to the campus of the Vrije Universiteit and close to Schiphol airport.

VUmc has the largest Level I trauma center in the country and an air medical services helicopter is affiliated with the hospital, covering three provinces.

Special units include: The VUmc has one of the highest publications in the Netherlands and has a well known reputation worldwide for class leading research.

[12] These are: The Center of Expertise on Gender Dysphoria (CEGD; or Kennis- en Zorgcentrum Genderdysforie, KZcG), a transgender clinic, is located at the VUmc.

[16] Initially, three patients brought charges[17][18] against the hospital and the production company for breaking doctor-patient confidentiality, illegal wiretapping and breach of Dutch privacy laws.