The specific use of the term "vaccine shedding" has risen to public prominence through anti-vaccine activists linked to misinformation related to COVID-19, who erroneously claim that COVID-19 vaccination can cause individuals to shed coronavirus spike protein and affect menstruation and fertility in women exposed to them.
[19] The route of infection is through contact with faeces, and some live vaccines, like the viruses they prevent, are shed in stool for up to 28 days.
[25] In dogs, vaccine-induced viral shedding has been observed with live attenuated Canine parvovirus vaccines.
[26] Regulatory authorities in the US and EU recommend that shedding data should be collected both during the development phase and clinical trials of a relevant product, such as gene therapy.
The estimated probability of transmission of vaccine virus within a contact group with a single LAIV recipient in this population was 0.58 percent.