Nicola Blackwood lost her seat in the snap 2017 general election and was replaced as a minister by Steve Brine.

During the COVID-19 pandemic in the United Kingdom, the minister was placed in charge of public health policy.

[1] The office of Parliamentary Under-Secretary of State for COVID-19 Vaccine Deployment was created later and was held by Nadhim Zahawi from 28 November 2020 to 15 September 2021.

[5] After the 2024 United Kingdom general election, Andrew Gwynne would be named as the new Labour Parliamentary Under-Secretary of State for Public Health and Prevention.

In February 2025, after Gwynne was dismissed by the government, Ashley Dalton would be named as the new minister.