Vaginal lubrication

The findings suggest that VIP may participate in the control of the local physiological changes observed during sexual arousal: genital vasodilation and an increase in vaginal lubrication.

Vaginal dryness can also be a symptom of Sjögren syndrome (SS), a chronic autoimmune disorder in which the body destroys moisture-producing glands.

Certain medications, including some over-the-counter antihistamines, as well as life events such as pregnancy, lactation, menopause, aging or diseases such as diabetes, will inhibit lubrication.

In seemingly rare cases, selective serotonin reuptake inhibitors (SSRIs) have been reported to cause a long-lasting iatrogenic disorder known as post-SSRI sexual dysfunction, the symptoms of which include reduced vaginal lubrication in females.

[9] Vaginal estrogen, which includes creams, pills, rings, and inserts, is more commonly prescribed due to its lower risk.

DHEA (prasterone) is a promising alternative that enhances vaginal health with minimal side effects and does not significantly alter hormone levels.

[8][10] Non-hormonal vaginal lubricants and moisturizers, which have minimal side effects and are easy to obtain, are the primary recommendation, especially for those contraindicated for hormone treatments.

[12] Lifestyle modifications can also alleviate vaginal dryness; quitting smoking, reducing alcohol intake, and maintaining a healthy weight is beneficial.

[8] Additionally, regular sexual activity can enhance tissue health and moisture levels, further aiding in symptom relief.