The last ruler of the Kingdom of Andrantsay was Andriamanalinarivo who was on the throne when Imerina king Andrianampoinimerina conquered the area with the help of the young prince Radama at the beginning of the 19th century.

[2] The vast majority of the population belongs to the Merina ethnic group.

There is an important textile industry and it is the principal bassin of legume production of the island.

It borders the region of Bongolava in the northwest, Itasy in the north, Analamanga in the northeast, Alaotra Mangoro and Atsinanana in the east, Amoron'i Mania in the south, and Menabe to the west.

A number of precious minerals are found in Vakinankaratra, including Ferrocolumbite, Liddicoatite, and Londonite.