The Boesio is a river (intermittent stream) in Valcuvia, a valley in the north of the province of Varese, Lombardy, Italy.

It rises near Cuveglio and flowing in an east–west direction before entering Lake Maggiore at Laveno-Mombello.

The river's course takes it through the communes of Cuveglio, Cuvio, Casalzuigno, Azzio, Brenta, Gemonio, Cittiglio and Laveno-Mombello.

Fish found in the river include Salmonidae and Cyprinidae, in particular brown trout and vairone (Leuciscus souffia).

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