It runs from Vesterbrogade in the north to Sønder Boulevard in the south, intersecting Istedgade and Dybølsgade on the way.

Most of the street is lined with five-storey, late 18th-century apartment blocks but its northern end stands out from the surrounding neighbourhood with its low, detached buildings with small front gardens.

One of the properties, De Suhrske Friboliger, is listed on the Danish registry of protected buildings and places.

St. Johns Hospital was built on the coast at the southern end of present-day Valdemarsgade in the 17th century.

A property at the northern end of present-day Valdemarsgade was in 1731 owned by Royal Kitchen Inspector and Poultry Purveyor Christoffer Nelling and was grazed by geese.

Henriette Lund (1829–1909), a niece of Søren Kierkegaard, describes the garden in her posthumously published memoirs.

Actor at the Royal Danish Theatre Peter William Jerndorff (1842–1926), who grew up on the estate, has also described it in his memoirs.

He had plans to create a new road with "beautiful places for people of the upper classes who had their businesses inside the city".

5–9) was built in 1876–78 at the initiative of Ole Berendt Suhr to provide affordable accommodation for needy merchants and their widows.

No, 15 was built for Vesterbros KFUM, the local branch of the YMCA: It now houses Teatret Zeppelin, a theatre specializing in productions for children and families.