In 2002,[2] she became assistant editor to Editorial Art Director Mark Chiarello on titles such as Aquaman, Batman Black and White, and JLA.

[3][4] Soon afterward, in the period 2007–2010,[5] D'Orazio was repeatedly bullied and harassed online by Chris Sims, an independent blogger.

[6] It was announced at the 2008 San Diego Comic-Con that D'Orazio would be writing a five-part Cloak and Dagger limited series for Marvel.

[9] D'Orazio was President of Friends of Lulu,[10] a non-profit organization that promoted women comic book creators and readers.

[14] In 2015, when Chris Sims was hired as a writer for Marvel, D'Orazio wrote about his prior harassment and bullying of her.