Smaldone has been a PBS host and interviewer for WNET, WLIW, NJTV, and other public television stations, and a featured reporter on ABC for the Columbus Day Parade.

In 2022, she directed and was executive producer of the faith-based film The Thursday Night Club adapted from the novella and audio drama podcast written by Steven Manchester.

One of her favorite memories at WFUV, where she hosted her own Broadway show tunes program called “Showstoppers,” was the opportunity to interview composer Charles Strouse.

She was then offered two jobs: one working in PR at a summertime music festival sponsored by PepsiCo and another at Hartsdale-based radio station WFAS, owned by Frank A. Seitz.

After meeting her, Bob Bruno, the program director of WOR, suggested she send a demo tape to George Wolfson, General Manager of the soon-to-be new adult contemporary radio station, WLTW (Lite-FM).

Smaldone hosted and produced “two or three syndicated shows” for which she conducted a variety of interviews with celebrities like Paul McCartney, Elton John, Billy Joel, Lionel Richie, Cher, the Bee Gees, and Mariah Carey.

Shortly after their second successful interview, Mr. Stewart personally requested Smaldone to interview him for his 2003 concert special, “It Had to Be You: The Great American Songbook.” After 24 years at WLTW and many notable ventures, including co-presenting the 2000 Billboard Music Awards with Ryan Seacrest, and the 1996 Atlanta Summer Olympic Torch event in Rockefeller Center with Bob Costas, Smaldone felt it was time for a change.

In 2009, Smaldone became an adjunct instructor at The School of Visual Arts, where she teaches adults voice-over acting and hosting and interviewing skills.

Airing weekly on Saturday mornings from 9 to 10, the program has thus far featured interviews with Brenda Vaccaro, Laura Benanti, Susan Lucci, Stephen Schwartz, Dionne Warwick, and Michael Lomonaco and many others.

Smaldone's other notable roles include Kara Angelo, a character she created in the play she co-wrote, entitled “Spit it Out!” She has performed in several acclaimed Off-Broadway plays: “Spalding Gray: Stories Left to Tell” at the Minetta Lane Theatre, “Naked in a Fishbowl” at the Soho Playhouse, “Broadway’s Next Hit Musical” at The Triad, and “Girl Talk: The Musical” at the Midtown Theatre, has participated in several readings featuring celebrities like Mario Cantone, Ralph Macchio, and Ally Sheedy, and was an onstage celebrity guest in the Broadway hit, “The 25th Annual Putnam County Spelling Bee.” Smaldone has been in a relationship with Richard Steinhaus, Jr, since 2001.

Smaldone has received a wide array of accolades for her work in radio, hosting, media & film, charitable causes, and cancer awareness.