However, due to his numerous commitments, both national and international, he can no longer lecture full-time, but he holds a visiting professor role.

He undertook and led numerous other expeditions, such as: Lavinium, Forum Gallorum and Forte Urbano in Italy, Túcume (Peru), Har Karkom and other overseas locations.

[1] He has published many academic essays and articles and he has written several best-selling novels (amounting to a total of about 8 million copies sold worldwide).

[1] He has also written the screenplays for Marco d'Aviano and Gilgamesh and he has adapted Le Memorie di Adriano for cinema screening.

On 11 February 2021, Manfredi and fellow writer Antonella Prenner were found unconscious at his home in Rome, after suffering a domestic incident caused by an accidental gas leak.