Van Nuys Boulevard is a major north–south arterial road that runs through the central San Fernando Valley of Los Angeles County, California.

The boulevard was notable for its cruising lifestyle that was prevalent in the 1960s and 1970s, which was depicted in the 1979 film Van Nuys Blvd.

[5] Van Nuys Boulevard runs approximately eleven miles from the Santa Monica Mountains in Sherman Oaks at its southern terminus to the foothills of the western end of the San Gabriel Mountains in Lake View Terrace at its northern terminus.

It passes through the affluent community of Sherman Oaks, then continues through the community of Van Nuys, passing the numerous automobile dealerships in southern Van Nuys, then passing through the Van Nuys Municipal Center, the government center of the San Fernando Valley, then continuing north through Panorama City, past the old General Motors plant now converted into a shopping plaza called “The Plant,” before veering north east through the communities of Arleta and Pacoima, passing the San Fernando Gardens housing project, and ending in the foothills of the San Gabriel Mountains.

With its wide expanse through the heart of the San Fernando Valley, Van Nuys Boulevard became known from the 1950s through the 1970s as a center of teenage cruising.