Vandana Gupte is an Indian actress known for her work in Marathi stage productions along with television and film productions.

[2][3] Her most well-known TV role was as the domineering Nilambari Pandey in Zee TV's comedy serial Kareena Kareena.

[citation needed] She was a part of project done by Ashok Hande on Manik Varma named Manik Moti with support by Rani Varma and Bharti Achrekar after Manik Varma's death.

[citation needed] Vandana is the daughter of noted classical singer Manik Varma and Shri Amar Varma, and sister of Bharati Achrekar and Rani Varma.

[4] She is married to criminal defence lawyer Shirish Gupte.