[1][2][3] It is endemic to South Africa and found in southwestern and southern part of Western Cape Province to extreme southwestern Eastern Cape Province,[2] from Nieuwoudtville in the west to Humansdorp in the east, along the coastal flats and Cape Fold Mountains from the sea level to 1,500 m (4,900 ft) asl.

[1] Sand toads are morphologically similar to other Vandijkophrynus species, but can usually be distinguished by their unspotted white ventrum and bright yellow flush over the dorsal surfaces of their feet.

[3] Sand toads may emerge from their refuges to breed in winter, May–September, when heavy rains have saturated the soil and created pools lasting for many weeks.

[3] They breed in temporary depressions in sandy areas, and also in clay soils.

[1] The species is threatened by habitat loss and deterioration caused by coastal development, alien plants, and wetland drainage for urbanization and agriculture.