Vardges Hamazaspi Petrosyan was born in 1932 in the town of Ashtarak, where he spent his childhood, went to school and began writing his first verses.

In 1954, he graduated from the journalism department of Yerevan State University and started writing for several youth newspapers.

As a newspaper correspondent, he travelled throughout his native Armenia and the entire Soviet Union, from Yakutia in Eastern Siberia to Karelia in the northwest of the country.

He is best known for his novellas The Last Teacher (Verjin usutsiche, 1980), Years Lived and Unlived (Aprats yev chaprats tariner, 1970), the series of short stories Letters from the Stations of Childhood (Namakner mankutyan kayarannerits), Drugstore Ani (Deghatun "Ani", 1973), the essay series "Armenian Sketches" ("Haykakan eskizner"), and the play Heavy is the Hat of Hippocrates (Tsanr e Hipokrati glkharke, 1975).

Most of Petrosyan's works, such as The Half-Open Windows of the City (Kaghaki kisabats lusamutnere, 1964) and Drugstore Ani, have youth and its psychological features as their subject.

His articles, travelogues and literary reviews were published in the collection An Equation with Multiple Unknowns (Havasarum bazmativ anhaytnerov) in 1977.